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Page 75 60 Cognitive and Brain Development Foltz et al. Experiments that inhibited methylation enabled XY ES cells to express stable Xist RNA, implying that DNA methylation is required to repress Xist expres- Escape Xic Xic Xa Gene-poor G-dark band Waystation elements in gene-rich G-light band Escape Xic Xist RNA spreading via waystation elements Xist RNA stably associated with Xi Xi Key Figure 3 A third study found that Xist RNA was capable of associating with Xa in somatic cells under certain experimental conditions, but could not induce the chro- mosome to inactivate.
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